In hospitals, the prevalence of antibiotic use is very high, and highly correlated with many other factors which could be important in the expression of CDI. Similarly, the demographics of hospitalized patients population also differ significantly from that of the community. The hospital environment has very specific characteristics which are likely to be important determinants of infectious disease occurrence and transmission, such as clustering of susceptible hosts, increased possibility of environmental contamination, physical proximity and multiple person to person contacts. difficile infections (CDI) have been conducted in acute care hospitals, and many have been performed during outbreak situations. difficile was mostly recognised as a nosocomial pathogen, the majority of studies of clinical C.
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